| Panel name | NGS Hereditary cancer panel 1 |
|---|---|
| Panel method | WES-based NGS |
| Panel version ** | v5.2 |
| Panel quality *** | |
| Core-NL | No core-NL genes included |
| CNV analysis | No |
| Note | Coverage gegevens volgen nog. |
| Location | Location VUmc |
| Genes (63) | Quality | % coverage >30 | % coverage >20 | Core-NL | Note |
|---|---|---|---|---|---|
| ACD | |||||
| APC | |||||
| ATM | |||||
| AXIN2 | |||||
| BAP1 | |||||
| BARD1 | |||||
| BMPR1A | |||||
| BRCA1 | |||||
| BRCA2 | |||||
| BRIP1 | |||||
| CDC73 | |||||
| CDH1 | |||||
| CDK4 | |||||
| CDKN2A | |||||
| CHEK2 | |||||
| CTNNA1 | |||||
| DICER1 | |||||
| FH | |||||
| FLCN | |||||
| GREM1 | |||||
| HOXB13 | |||||
| MAX | |||||
| MEN1 | |||||
| MET | |||||
| MLH1 | |||||
| MSH2 | |||||
| MSH3 | |||||
| MSH6 | |||||
| MUTYH | |||||
| NF1 | |||||
| NF2 | |||||
| NTHL1 | |||||
| PALB2 | |||||
| PMS2 | |||||
| POLD1 | |||||
| POLE | |||||
| POT1 | |||||
| PRDM10 | |||||
| PRKAR1A | |||||
| PTCH1 | |||||
| PTEN | |||||
| RAD50 | |||||
| RAD51 | |||||
| RAD51C | |||||
| RAD51D | |||||
| RB1 | |||||
| RET | |||||
| RNF43 | |||||
| SDHA | |||||
| SDHAF2 | |||||
| SDHB | |||||
| SDHC | |||||
| SDHD | |||||
| SMAD4 | |||||
| SMARCB1 | |||||
| STK11 | |||||
| SUFU | |||||
| TMEM127 | |||||
| TP53 | |||||
| TSC1 | |||||
| TSC2 | |||||
| VHL | |||||
| WT1 |
| Indication(s) |
|---|
| Tumor syndromes |
** For information on previous versions of this panel, please contact the Genome Diagnostics Laboratory
*** NGS panel genes can be analyzed with different quality. More info about test quality type A, C or A/C