| Panel name | NGS Dyslipidemia |
|---|---|
| Panel method | Targeted NGS |
| Panel version ** | DLv5 |
| Panel quality *** | A |
| Core-NL | No core-NL genes included |
| CNV analysis | Yes |
| Note | incl. 2 SNPs in LPA (rs10455872 en rs3798220) |
| Location | Location AMC |
| Genes (29) | Quality | % coverage >30 | % coverage >20 | Core-NL | Note |
|---|---|---|---|---|---|
| ABCA1 | A | 100.0 | 100.0 | ||
| ABCG5 | A | 100.0 | 100.0 | ||
| ABCG8 | A | 100.0 | 100.0 | ||
| ANGPTL3 | A | 100.0 | 100.0 | ||
| APOA1 | A | 100.0 | 100.0 | ||
| APOA5 | A | 100.0 | 100.0 | ||
| APOB | A | 100.0 | 100.0 | ||
| APOC2 | A | 100.0 | 100.0 | ||
| APOC3 | A | 100.0 | 100.0 | ||
| APOE | A | 100.0 | 100.0 | ||
| CETP | A | 100.0 | 100.0 | ||
| CYP27A1 | A | 100.0 | 100.0 | ||
| CYP7A1 | A | 100.0 | 100.0 | ||
| GPD1 | A | 100.0 | 100.0 | ||
| GPIHBP1 | A | 100.0 | 100.0 | ||
| LCAT | A | 100.0 | 100.0 | ||
| LDLR | A | 100.0 | 100.0 | ||
| LDLRAP1 | A | 100.0 | 100.0 | ||
| LIPA | A | 100.0 | 100.0 | ||
| LIPC | A | 100.0 | 100.0 | ||
| LIPG | A | 100.0 | 100.0 | ||
| LMF1 | A | 100.0 | 100.0 | ||
| LPL | A | 100.0 | 100.0 | ||
| MTTP | A | 100.0 | 100.0 | ||
| MYLIP | A | 100.0 | 100.0 | ||
| PCSK9 | A | 100.0 | 100.0 | ||
| SAR1B | A | 100.0 | 100.0 | ||
| SCARB1 | A | 100.0 | 100.0 | ||
| SLCO1B1 | A | 100.0 | 100.0 |
| Indication(s) |
|---|
| Dyslipidemia (incl. Familial Hypercholesterolemia/FH) |
| Metabolic disorders, general |
** For information on previous versions of this panel, please contact the Genome Diagnostics Laboratory
*** NGS panel genes can be analyzed with different quality. More info about test quality type A, C or A/C