| Panel name | NGS Breast and ovarian cancer – HCS panel |
|---|---|
| Panel method | Targeted NGS |
| Panel version ** | v2.0 |
| Panel quality *** | A |
| Core-NL | No core-NL genes included |
| CNV analysis | Yes |
| Location | Location VUmc |
| Genes (13) | Quality | % coverage >30 | % coverage >20 | Core-NL | Note |
|---|---|---|---|---|---|
| ATM | A | 100 | 100 | ||
| BARD1 | A | 100 | 100 | ||
| BRCA1 | A | 100 | 100 | ||
| BRCA2 | A | 100 | 100 | ||
| BRIP1 | A | 100 | 100 | ||
| CDH1 | A | 100 | 100 | ||
| CHEK2 | A | 100 | 100 | incl. c.1100del | |
| CTNNA1 | A | 100 | 100 | ||
| PALB2 | A | 100 | 100 | ||
| PTEN | A | 100 | 100 | ||
| RAD51C | A | 100 | 100 | ||
| RAD51D | A | 100 | 100 | ||
| STK11 | A | 100 | 100 |
| Indication(s) |
|---|
| Breast cancer |
| Breast-ovarian cancer |
| Ovarian cancer |
** For information on previous versions of this panel, please contact the Genome Diagnostics Laboratory
*** NGS panel genes can be analyzed with different quality. More info about test quality type A, C or A/C