NGS Arrhythmia

Panel name	NGS Arrhythmia
Panel method	Targeted NGS
Panel version **	SCDv10;ARTMtypeAv9
Panel quality ***	A
Core-NL	No core-NL genes included
CNV analysis	Yes
Location	Location AMC

Genes (51)	Quality	% coverage >30	% coverage >20	Core-NL	Note
ABCC9	A	100	100
AKAP9	A	100	100
ALG10B	A	100	100
ANK2	A	100	100
ANK3	A	100	100
CACNA1C	A	100	100
CALM1	A	100	100
CALM2	A	100	100
CALM3	A	100	100
CASQ2	A	100	100
CAV3	A	100	100
DPP6	A	100	100
GJA5	A	100	100
GJC1	A	100	100
GNB2	A	100	100
HCN4	A	100	100
HEY2	A	100	100
HOOK3	A	100	100
IRX3	A	100	100
JPH2	A	100	100
KCNA5	A	100	100
KCNAB2	A	100	100
KCND3	A	100	100
KCNE1	A	100	100
KCNE2	A	100	100
KCNH2	A	100	100
KCNJ2	A	100	100
KCNQ1	A	100	100
LAMP2	A	100	100
LMNA	A	100	100
MYL4	A	100	100
NKX2-5	A	100	100
NPPA	A	100	100
PKP2	A	100	100
PLN	A	100	100
POPDC2	A	100	100
PPA2	A	100	100
PRKAG2	A	100	100
RANGRF	A	100	100
RRAD	A	100	100
RYR2	A	100	100
SCN5A	A	100	100
SLC4A3	A	100	100
SNTA1	A	100	100
TBX20	A	100	100
TCAP	A	100	100
TECRL	A	100	100
TNNI3K	A	100	100
TNNT2	A	100	100
TRDN	A	100	100
TRPM4	A	100	100

Indication(s)
Atrial fibrillation
Atrial standstill
Bradychardia
Brugada syndrome
Cardiac arrhythmia
Catecholaminergic polymorphic ventricular tachycardia CPVT
Conduction defects
Long QT syndrome LQT
Short QT syndrome
Sick sinus syndrome
Sudden cardiac death
Ventricular fibrillation

** For information on previous versions of this panel, please contact the Genome Diagnostics Laboratory

*** NGS panel genes can be analyzed with different quality. More info about test quality type A, C or A/C